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A large school district in Cincinnati partnered with their local health department and children’s hospital to develop mitigation procedures as children returned to school. These mitigation procedures successfully limited school-based spread of COVID-19 by combining best practices in rapid testing, contact tracing, and early isolation. Procedures were regularly revisited and updated in an iterative process to respond to new information and circumstances.

The Oregon county with the first confirmed COVID-19 case in the United States began its response in the earliest days of the pandemic. The county’s Emergency Operations Center wanted to center equity in its response and did so by rapidly creating new positions on the team: an Equity Officer, an Equity Technical Advisor, and a Language Access Coordinator. It also established an Equity Team within the center. This allowed responses to quickly identify and respond to population needs, especially those in communities of color experiencing disproportionate impacts of disease spread and burden.

This article discusses the process used by the New York City Health Department to prioritize populations for access to the first round of COVID-19 vaccines. The city’s process was guided by input gathered during five public meetings. During these meetings, participants emphasized the need to prioritize health equity, examining the broad swatch of personal and societal factors that make people more or less susceptible to severe COVID-19 disease.

This article discusses what can be learned from the response to COVID-19 within the United States-Affiliated Pacific Islands (USAPIs). Rates of COVID-19 in this region were much lower than those in the mainland US, despite fewer public health resources. The article credits this to strong partnership and collaboration with neighboring islands, the mainland US, and the federal government; strong regional information sharing; creating and nurturing local and regional trust; and trust regionally; and decisive and aggressive quarantine practices.

This case study of the VA Puget Sound Health Care System highlights effective practices for increasing vaccine uptake among vulnerable populations of veterans. This included targeting outreach to people based on race/ethnicity and the presence of risk factors for severe COVID-19 disease. The VA Puget Sound Health Care System used multiple modalities of communications and collaborated with community leaders in order to increase vaccine rates among people in underserved areas.

Johns Hopkins Health System and Baltimore community organizations collaborated to establish a bilingual COVID-19 hotline and implement free COVID-19 testing. When a vaccine became available, partnerships made within these efforts were leveraged and the coalition partnered with the state. This community-based approach was effective at expanding access to the COVID-19 vaccine among low-income Latino immigrants.

The Connecticut Department of Public Health Contact Tracing Program implemented a Community Outreach Specialist program to support COVID-19 contact tracing among vulnerable communities with high proportions of Spanish, Portuguese, Polish, or Haitian Creole-speaking residents.

The Public Health-Seattle and King County evaluated its case investigation and contract tracing program for effectiveness and found that contract tracing helped nearly three in four people surveyed stay in isolation. This demonstrates the value of contact tracing and case investigation as a public health tool for COVID-19 mitigation.

In 2022, the Los Angeles County Department of Public Health piloted an innovative and barrier-reducing test-to-treat method. This approach used digital test results to submit a positive COVID-19 result and provided COVID-19 patients with Paxlovid. By adopting this rapid-response digital technology approach, public health practitioners were able to improve treatment access and reduce health disparities.

The NYC Department of Health and Mental Hygiene partnered with 45 businesses or faith-based organizations in the Northeast Bronx to increase COVID-19 and flu vaccine knowledge and uptake in predominantly Black and Hispanic areas. The program disseminated health information through trusted community leaders to address vaccine hesitancy. ZIP codes with higher involvement in the program showed greater increases in vaccination rates.