Practices that show potential to achieve desirable public health outcomes in a specific real-life setting and are in the process of generating evidence of effectiveness or may not yet be tested.

Risk factors for severity of COVID-19 in hospital patients age 18-29 years

Sandoval, A., Nguyen, D. T., Vahidy, F. S., Gravis, E. A.

Release Date:

Peer Review Study

Data Collection and Analysis
Healthcare Access and Quality
Tools Included
Outside U.S.
Network of people

Partnerships and Collaboration

A retrospective registry-based chart review examined the various demographic and clinical risk factors associated with COVID-19 severity among patients aged 18-29. The study was done within a metropolitan health care system in Houston, TX. In the cohort of 1,853 young adult patients diagnosed with COVID-19 infection at a hospital encounter, including 226 pregnant women, 1,438 (78%) scored 0 on the Charlson Comorbidity Index, and 833 (45%) were obese (≥30 kg/m2). Within 30 days of their diagnostic encounter, 316 (17%) patients were diagnosed with pneumonia, 148 (8%) received other severe disease diagnoses, and 268 (14%) returned to the hospital after being discharged home. In multivariate logistic regression analyses, increasing age, male gender, Hispanic ethnicity, obesity, asthma history, congestive heart failure, cerebrovascular disease, and diabetes were predictive of severe disease diagnoses within 30 days. Non-Hispanic Black race, obesity, asthma history, myocardial infarction history, and household exposure were predictive of 30-day readmission.

Resource Details

Outcomes of Interest

Reduction of Health Disparities

Priority Population(s)

Youth and Young Adults

Setting(s) of Implementation


Geographic Area of Implementation

Implementation Period